The Future of ePRO · Oncology

Cancer care goes quiet between visits.
We don't.

AsclepiusAI keeps cancer patients and their care teams connected between visits — so problems are caught early, understood clearly, and treated before they become emergencies.

Backed by randomized-trial evidence · Built for community oncology
Guided Journal No clinical forms. Just talking.
Care team notified Before it becomes an ER visit.

The cost of silence between visits

0M+
new U.S. cancer diagnoses every year
$0B
projected U.S. cancer costs by 2030
0%
of cancer ED visits are potentially preventable
~0%
of oral therapy patients are nonadherent

The Problem

The most expensive part of cancer care is the part nobody sees.

Patients are seen for minutes at a time, weeks apart. What happens in between — escalating symptoms, missed doses, unanswered questions — goes unseen until the only option left is the ER.

Symptoms escalate quietly

Issues that a phone call could have managed at home grow silently until they end in an emergency room — and roughly one in four of those visits ends in an unplanned hospitalization.

3.21M preventable ED visits in 2019 alone

Clinicians are drowning

Oncology inbox volume rose 19% and patient messages rose 34% in three years. Only 5.6% of U.S. oncologists practice in rural areas where the need is greatest.

After-hours EHR work at record highs

Patients navigate alone

Half of patients on oral cancer therapies don't take their medication as prescribed — driven by side effects, confusion, and cost. Nonadherence is directly linked to progression and premature death.

~50% oral therapy nonadherence

The Platform

Two arms. One loop. Zero silence.

A patient-first platform that turns the quiet time between visits into structured, actionable care — light enough for a small clinic to adopt in weeks.

AMI · Artificial Medical Intelligence

The patient's personal guide

  • Explains diagnosis, treatment, and medications in plain language
  • Prompts symptom reports based on memory and clinical context
  • Helps patients put concerns into words their physician can act on
  • Prepares patients for appointments — so visit time is spent on care, not catch-up

PRO Monitor

Symptom intake & monitoring

  • Captures patient-reported outcomes through a guided journal — no clinical forms
  • Flags deterioration before the next appointment
  • Delivers organized, prioritized reports — not unmanaged message queues
  • Keeps patients engaged and care teams informed, every day

The clinical intelligence loop

Every interaction deepens the platform's understanding of each patient. Better intelligence enables earlier intervention — and earlier intervention is everything in oncology.

Patient voice Made actionable Care team responds Loop deepens

Meet AMI

A guide who never forgets, never sleeps, and never talks down to you.

Patients forget 40–80% of what they're told in appointments. AMI is there at 2 a.m. when the question actually comes up — answering in plain language, watching for warning signs, and turning worry into a structured report a clinician can act on.

"I turn 'I've been feeling off lately' into data a doctor can act on."
AMIArtificial Medical Intelligence · Demo
My doctor said I'll start "adjuvant chemo" next week. I was too embarrassed to ask what that means.
Never be embarrassed with me — that's what I'm here for. "Adjuvant" just means after surgery: it's chemo given to catch any cancer cells that might be left behind, lowering the chance it comes back.
Want me to add this to your appointment prep? You could ask Dr. Patel how many cycles to expect — I'll help you remember.
Yes please. Also my hands have been tingling since yesterday…
That's worth logging — tingling can be a side effect your team will want to know about early. I've drafted a symptom report. Send it to your care team?

The Evidence

This isn't a thesis. It's one of the most validated interventions in oncology.

Between-visit symptom reporting has been proven in landmark randomized trials — AsclepiusAI adds the engagement layer those systems lacked.

+5 mo

longer median survival for patients who reported symptoms electronically between visits

Basch et al., JAMA 2017
−16%

emergency visits across 52 community oncology practices in the national PRO-TECT trial

Basch et al., 2025
$1,146

saved per patient per month — nearly 10% of total cost — driven by 39% fewer hospitalizations

Texas Two-Step, JCO OP 2023
77%

of patients reported better communication with their care team

PRO-TECT, 2025
The missing piece was engagement. Earlier systems proved the model but treated patients as data sources. AsclepiusAI builds the opposite way — a platform patients actually want to use, powered by AI that responds in seconds, not voicemail queues.

Who Benefits

Built for every side of the visit.

Patients

Confidence between visits

  • A simple daily companion to record symptoms, questions, and concerns
  • Plain-language education about their cancer, treatment, and what to expect
  • Urgent concerns reach the care team in real time — no messy portal messages, no waiting for the next visit
2 a.m.

When the scary question comes up, AMI answers — accurately, instantly, kindly.

Clinics

Capacity without headcount

  • Structured, prioritized patient reports instead of unmanaged message queues
  • Early visibility into deterioration between appointments
  • Built for small teams — no enterprise IT, no heavy implementation, live in weeks
Weeks

From signature to go-live. No EHR customization project. No integration team.

Providers & Insurers

Lower total cost of care

  • Remote monitoring cut total cost of care by $1,146 per patient per month in community oncology
  • Fewer preventable ED visits and hospitalizations — the largest avoidable line item in oncology spend
  • Better treatment adherence — directly tied to fewer hospitalizations and better outcomes
−10%

Total cost of care in a deployed Medicare oncology population.

Built to Pay for Itself

Affordability isn't a feature. It's the architecture.

Medicare and commercial payers already reimburse remote patient monitoring and care-management work. AsclepiusAI's outputs — symptom reports, monitoring records, time tracking, escalation documentation — are generated to meet those reimbursement requirements from day one.

Recurring reimbursement revenue that can offset — and exceed — subscription cost
Payer-ready documentation — PCM, CCM, digital E/M, and oncology navigation pathways
Advisors from insurance & claims operations — built to meet payer criteria on first submission

For Investors

The infrastructure layer for oncology — and infrastructure gets acquired.

We're building two compounding assets: a patient engagement platform that lowers cost of care, and a proprietary longitudinal oncology dataset that grows more valuable with every patient enrolled.

Beachhead Market

$20M–$120M SAM

300–600 Midwest rural & community oncology clinics — high need, operationally strained, overlooked by competitors.

Expansion

$500M–$2B+

5,000–8,000 community oncology clinics nationally — same pain points, at scale, with a trained clinical intelligence layer competitors can't replicate.

Comparables

$1.9B · $18.5B

Flatiron Health → Roche (oncology real-world data). Livongo → Teladoc (engagement at scale). Oncology is the larger, more expensive problem.

Working MVP — not a prototype Pilot conversations active with CMU-affiliated oncology CMU pitch competition finalist $30–40 PPPM recurring revenue model Raising $1.5–1.75M seed · 18 months runway

Join Us

The future of ePRO starts between visits.

Be among the first clinics and partners to bring evidence-backed, patient-first oncology engagement to the communities that need it most.

AMI · Your Guide